I’m proud to share that our latest review article for the European Partnership for the Assessment of Risks from Chemicals (PARC) has been published in Frontiers in Toxicology!

📖 Read the full article: https://doi.org/10.3389/ftox.2024.1331803

Titled “Chemical respiratory sensitization—Current status of mechanistic understanding, knowledge gaps and possible identification methods of sensitizers,” this review presents a deep dive into:

• A curated reference list of known respiratory sensitizers

• Regulatory insights from the C&L Inventory

• Current limitations in testing methods

• Emerging concepts like adverse outcome pathways (AOPs)

• New Approach Methodologies (NAMs) for hazard identification

Respiratory sensitization remains a complex and under-addressed area in toxicology. Our review identifies where progress is being made—and where major challenges remain, especially for predictive modeling and regulatory acceptance.

This was a collaborative effort with experts from across Europe and a pleasure to co-author alongside Lucia Parráková and many dedicated colleagues. Thanks to the entire PARC consortium for making this possible.

🧪 This article is part of the special issue: PARC – Focus on New Approach Methodologies in Risk Assessment

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